SCHEMBL577075

SCHEMBL577075

Cc1cc(OCCO)c(C(C)(C)C)cc1-c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.35
PNMT P11086 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KCNH2 Q12809 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577662 0.85 AR (0.43) ARPNMTNPC1RAB9AKDM4E
Fluorene SCHEMBL28408646 0.84 AR (0.42) ARPNMTNPC1RAB9AKDM4E
SCHEMBL29099228 0.81 ALDH1A1 (0.36) ARPNMTNPC1RAB9AKDM4E
SCHEMBL577513 0.79 TLR8 (0.39) ARPNMTNPC1RAB9AMEN1
SCHEMBL30352842 0.77 LMNA (0.47) ARPNMTNPC1RAB9AKDM4E
SCHEMBL21380737 0.77 LMNA (0.47) ARPNMTNPC1RAB9AKDM4E
SCHEMBL8068048 0.76 PNMT (0.46) ARPNMTNPC1RAB9AALDH1A1
SCHEMBL577260 0.76 PNMT (0.39) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL29216755 0.74 TLR8 (0.42) PNMTNPC1RAB9AMEN1KMT2A
SCHEMBL30478398 0.74 PNMT (0.36) ARPNMTNPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed