Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | PDE4A | P27815 | 1/20 | 0.73 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.71 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465076 | 1.00 | CHRM1 (0.73) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL3147555 | 0.84 | CHRM1 (0.75) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL31006096 | 0.84 | CHRM1 (0.75) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| Ibuproxam SCHEMBL10428212 | 0.84 | CHRM1 (1.00) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| Ibuproxam SCHEMBL8722617 | 0.84 | CHRM1 (1.00) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL19953817 | 0.84 | CHRM1 (0.75) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| Ibuproxam SCHEMBL24896 | 0.84 | CHRM1 (1.00) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL3142734 | 0.84 | CHRM1 (0.75) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL1820667 | 0.83 | CHRM1 (0.69) | CHRM1PDE4ACXCR1CXCR2EPHX1 | |
| SCHEMBL13952025 | 0.83 | CXCR1 (1.00) | CHRM1PDE4ACXCR1CXCR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066289-A1 | BIGUANIDE DERIVATIVE OF IBUPROFEN AND PROCESS OF PREPARATION THEREOF | BVDU'S POONA COLLEGE OF PHARMACY (IN) | 2025-02-27 | — | — | US | claimed |
| US-20250066289-A1 | BIGUANIDE DERIVATIVE OF IBUPROFEN AND PROCESS OF PREPARATION THEREOF | BVDU'S POONA COLLEGE OF PHARMACY (IN) | 2025-02-27 | — | — | US | disclosed |
| US-12234205-B1 | Sulfonylhydrazide derivatives as anticancer agents | KING SAUD UNIVERSITY (SA) | 2025-02-25 | — | — | US | disclosed |
| CN-116178444-A | Bivalent platinum complex and derivative thereof, preparation method, pharmaceutical composition and application | 东南大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114835656-A | 1,3, 4-oxadiazole ethyl acetate and synthesis method thereof | 天津中医药大学 | 2022-08-02 | — | — | CN | disclosed |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S.A. (BR) | 2012-05-10 | — | — | US | disclosed |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S.A. (BR) | 2012-05-10 | — | — | US | disclosed |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S.A. (BR) | 2012-05-10 | — | — | US | disclosed |
| EP-2418200-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF- MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S. A. (BR) | 2012-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234205-B1 | Sulfonylhydrazide derivatives as anticancer agents | FAAH, FAAH2, ABCC4 | CHRM1 4885/4885PDE4A 1901/4885CXCR1 3654/4885 |
| US-20250066289-A1 | BIGUANIDE DERIVATIVE OF IBUPROFEN AND PROCESS OF PREPARATION THEREOF | SLC5A2, MYD88, MB | CHRM1 4353/4885PDE4A 1272/4885CXCR1 3071/4885 |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | TNF, PER2, CRY1 | CHRM1 1629/4885PDE4A 340/4885CXCR1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.