Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.41 |
| ▸ | NOS3 | P29474 | 7/20 | 0.41 |
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431809 | 0.76 | — | — | |
| SCHEMBL6429736 | 0.70 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL11407479 | 0.69 | TDP1 (0.46) | NOS2NOS3NOS1CRHR1 | |
| SCHEMBL6444145 | 0.68 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL11481158 | 0.66 | NOS3 (0.48) | NOS2NOS3NOS1 | |
| SCHEMBL11403187 | 0.62 | SLC29A1 (0.43) | NOS2NOS3NOS1 | |
| SCHEMBL94111 | 0.61 | — | — | |
| SCHEMBL31324837 | 0.61 | — | — | |
| Bromide SCHEMBL5755666 | 0.59 | NOS2 (0.95) | NOS2NOS3NOS1 | |
| SCHEMBL5430796 | 0.58 | CRHR1 (0.49) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725562-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005085253-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-09-15 | — | — | WO | disclosed |