Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | BLVRB | P30043 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005116 | 0.81 | ERN1 (0.52) | APPTTRERN1MEN1HTT | |
| SCHEMBL5463920 | 0.80 | PTPN1 (0.50) | PTPN1PTPN6PTPN2TP53FNTA | |
| SCHEMBL5778489 | 0.79 | ALDH1A1 (0.43) | APPERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL31497642 | 0.77 | PTPN1 (0.69) | APPTTRPTPN1PTPN6PTPN2 | |
| SCHEMBL10763255 | 0.77 | PTPN1 (0.46) | PTPN1PTPN6PTPN2FNTAFNTB | |
| SCHEMBL1984171 | 0.77 | HMGB1 (0.55) | TTRPTPN1PTPN6PTPN2ALDH1A1 | |
| SCHEMBL4756919 | 0.77 | PTPN1 (0.69) | APPTTRPTPN1PTPN6PTPN2 | |
| SCHEMBL7962088 | 0.75 | XDH (0.50) | APPTTRERN1FNTAFNTB | |
| SCHEMBL15524696 | 0.75 | TTR (0.47) | TTRPTPN1TP53AKR1C4AKR1C3 | |
| SCHEMBL29396210 | 0.75 | TTR (0.56) | TTRPTPN1PTPN6PTPN2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | APP 1/4885TTR 12/4885PTPN1 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.