SCHEMBL1005116

SCHEMBL1005116

O=Cc1cc(I)c(O)c(I)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.52
TTR P02766 2/20 0.50
NAT1 P18440 4/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
APP P05067 1/20 0.42
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41
ALB P02768 1/20 0.41
XDH P47989 1/20 0.41
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740604 0.91 ERN1 (0.45) ERN1TTRNAT1MEN1LMNA
SCHEMBL7962088 0.88 XDH (0.50) ERN1TTRNAT1MEN1LMNA
SCHEMBL24981909 0.84 ERN1 (0.44) ERN1TTRNAT1KDM4EPTGS2
SCHEMBL28702107 0.84 CHEK1 (0.46) ERN1TTRXDH
SCHEMBL1002420 0.84 APP (0.64) ERN1MEN1LMNAHTTKMT2A
SCHEMBL29696004 0.84 APP (0.64) ERN1MEN1LMNAHTTKMT2A
SCHEMBL5367228 0.84 GABBR2 (0.51) ERN1MEN1LMNAHTTKMT2A
SCHEMBL5777093 0.81 APP (0.45) ERN1TTRMEN1HTTKMT2A
SCHEMBL5778489 0.80 ALDH1A1 (0.43) ERN1MEN1LMNAKMT2AAPP
SCHEMBL6801555 0.80 KDM4E (0.60) MEN1LMNAKMT2AAPPKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119970171-A Blood vessel puncture positioning membrane for DSA guidance and preparation process thereof 盐城市中医院 2025-05-13 CN claimed
CN-119977868-A Mitochondria-targeted photosensitizer capable of being activated by glutathione and preparation method and application thereof 无锡太湖学院 2025-05-13 CN claimed
CN-119265178-A Near infrared light activated protein proximity labeling method 湖南大学 2025-01-07 CN claimed
CN-118043043-A Benzofuranyl hydroxy phenyl ketone derivative compound or pharmaceutically acceptable salt thereof 因诺沃治疗有限公司 2024-05-14 CN claimed
CN-118005556-A COX-2 targeted inhibition photosensitizer capable of activating tumor cell apoptosis and preparation method and application thereof 大连理工大学 2024-05-10 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-117069581-A Synthesis method of 2, 6-diiodo-4-vinyl phenyl acetate 成都东凯芯半导体材料有限公司 2023-11-17 CN claimed
CN-114890976-B Rhodamine-based AIE photosensitizer for selective killing of gram-positive bacteria, and preparation method and application of gel dressing of rhodamine-based AIE photosensitizer 大连理工大学 2023-08-18 CN claimed
CN-113956190-B Cell targeting photosensitizer capable of activating tumor cell apoptosis and preparation method and application thereof 大连理工大学 2023-05-02 CN claimed
WO-2007019930-A1 AGENT FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-02-22 WO claimed
WO-2006131163-A1 MULTICOMPONENT COMPOSITION FOR DYEING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO claimed
WO-2006119821-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119818-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119820-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006077039-A1 AGENTS FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-07-27 WO claimed
WO-2006040015-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-04-20 WO claimed
WO-2006029687-A1 SUBSTANCE FOR DYEING KERATINIC FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-03-23 WO claimed
EP-0488860-B1 Method for the production of polyalkoxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1995-10-11 EP claimed
EP-0423010-B1 METHOD FOR THE PRODUCTION OF ALKOXYBENZALDEHYDES RHONE-POULENC CHIMIE (FR) 1993-09-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ERN1 4459/4885TTR 1170/4885NAT1 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.