Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224548 | 0.85 | TAAR1 (0.72) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL27679990 | 0.84 | MAOA (0.50) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL10952838 | 0.82 | GFER (0.47) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| Hydrochloric Acid SCHEMBL3668004 | 0.82 | BLM (0.74) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| Hydrochloric Acid SCHEMBL3168355 | 0.82 | BLM (0.74) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| Iodide SCHEMBL29101247 | 0.82 | TAAR1 (0.68) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL1533389 | 0.78 | TAAR1 (0.39) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL232738 | 0.77 | — | — | |
| SCHEMBL6532602 | 0.77 | MAOB (0.73) | TAAR1HTR2ACYP2A6CYP1A2KDM4E | |
| SCHEMBL143553 | 0.77 | GFER (0.77) | TAAR1HTR2ACYP2A6CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | claimed |
| CN-117042783-A | Implant device using chemically cross-linked alginic acid | 持田制药株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-116874636-A | Novel cross-linked alginic acid | 持田制药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-114302749-A | Transplanting device using chemically crosslinked alginic acid | 持田制药株式会社 | 2022-04-08 | — | — | CN | disclosed |
| CN-112236457-A | Novel cross-linked alginic acid | 持田制药株式会社 | 2021-01-15 | — | — | CN | disclosed |
| CN-105001096-B | A kind of method for preparing 4 amino N alkylbenzylamines | 沈阳化工研究院有限公司 | 2017-07-21 | — | — | CN | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S.A. (BR) | 2012-05-10 | — | — | US | disclosed |
| CN-1038839-C | Process for preparation of cyclic amine compounds | EISAI CO LTD (JP) | 1998-06-24 | — | — | CN | disclosed |
| CN-1034015-C | Process to prepare cycloamine compounds | EISAI CO LTD (JP) | 1997-02-12 | — | — | CN | disclosed |
| CN-1024547-C | Preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| CN-1073939-A | A kind of preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1993-07-07 | — | — | CN | disclosed |
| CN-1071417-A | The preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1993-04-28 | — | — | CN | disclosed |
| CN-1030752-A | Preparation method of cyclic amine compound | EISAI CO LTD (JP) | 1989-02-01 | — | — | CN | disclosed |
| US-4428960-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4388310-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1983-06-14 | — | — | US | disclosed |
| US-4374849-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-4217453-A | BACTERICIDES, ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | TAAR1 4223/4885HTR2A 2997/4885CYP2A6 1344/4885 |
| US-20120115817-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | TNF, PER2, CRY1 | TAAR1 2640/4885HTR2A 1622/4885CYP2A6 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.