Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777356 | 0.86 | AAK1 (0.35) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL5912671 | 0.82 | IMPDH2 (0.34) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5774833 | 0.76 | GPR119 (0.36) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5779113 | 0.75 | AAK1 (0.40) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5775952 | 0.72 | NPC1 (0.49) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5779456 | 0.68 | GPR119 (0.45) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5777062 | 0.67 | NPC1 (0.44) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5776483 | 0.66 | CDK1 (0.49) | AAK1PKMNPC1KDM4ELMNA | |
| SCHEMBL5776708 | 0.65 | ROCK2 (0.41) | PKMNPC1KDM4ELMNARAB9A | |
| SCHEMBL5778725 | 0.65 | KDM4E (0.48) | AAK1PKMNPC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |