Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3859178 | 0.99 | SIGMAR1 (0.65) | SIGMAR1KDM4EHRH3ALDH1A1KMT2A | |
| SCHEMBL22066893 | 0.88 | HRH2 (0.65) | SIGMAR1KDM4EHRH3ALDH1A1KMT2A | |
| SCHEMBL30969213 | 0.85 | DRD3 (0.59) | KDM4EHRH3ALDH1A1 | |
| SCHEMBL3026592 | 0.84 | PSMB1 (0.75) | KDM4EHRH3 | |
| SCHEMBL30969292 | 0.83 | HRH3 (0.54) | HRH3 | |
| SCHEMBL30969262 | 0.83 | HRH3 (0.65) | KDM4EHRH3 | |
| SCHEMBL30969263 | 0.83 | PSMB1 (0.78) | KDM4EHRH3ALDH1A1 | |
| SCHEMBL3866360 | 0.81 | SIGMAR1 (0.71) | SIGMAR1KDM4EHRH3KMT2A | |
| SCHEMBL4022248 | 0.81 | HTR2C (0.54) | KDM4EALDH1A1KMT2A | |
| SCHEMBL491570 | 0.81 | HRH3 (0.72) | SIGMAR1KDM4EHRH3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708698-A1 | 3-(4-PIPERIDINE-1YLMETHYL-PHENYL)-PROPION ACID-PHENYLAMIDE-DERIVATIVES AND RELATED COMPOUNDS USED IN THE FORM OF MCH ANTAGONISTS (MELANINE CONCENTRATING HORMONE) FOR TREATING EATING DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005063239-A9 | 3-(4-PIPERIDINE-1YLMETHYL-PHENYL)-PROPION ACID-PHENYLAMIDE-DERIVATIVES AND RELATED COMPOUNDS USED IN THE FORM OF MCH ANTAGONISTS (MELANINE CONCENTRATING HORMONE) FOR TREATING EATING DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2006-03-09 | — | — | WO | disclosed |
| WO-2005063239-A1 | 3-(4-PIPERIDINE-1YLMETHYL-PHENYL)-PROPION ACID-PHENYLAMIDE-DERIVATIVES AND RELATED COMPOUNDS USED IN THE FORM OF MCH ANTAGONISTS (MELANINE CONCENTRATING HORMONE) FOR TREATING EATING DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-07-14 | — | — | WO | disclosed |