Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780400 | 0.88 | ALB (0.53) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5778781 | 0.80 | ALB (0.55) | ALBSMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL5774563 | 0.78 | ALB (0.69) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5780106 | 0.78 | ALB (0.57) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27569880 | 0.78 | ALB (0.57) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5778029 | 0.77 | ALB (0.51) | ALBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5776928 | 0.74 | ALB (0.57) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5776363 | 0.74 | ALB (0.66) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27588013 | 0.74 | ALB (0.66) | ALBSNCAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5778188 | 0.73 | ALB (0.52) | ALBSNCAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |