Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 7/20 | 0.45 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780106 | 0.90 | ALB (0.57) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27569880 | 0.90 | ALB (0.57) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5778188 | 0.79 | ALB (0.52) | ALBMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5779807 | 0.79 | ALB (0.61) | ALBPLAUPLAT | |
| SCHEMBL5778350 | 0.79 | ALB (0.57) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5778781 | 0.79 | ALB (0.55) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5780400 | 0.77 | ALB (0.53) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5779175 | 0.77 | ALB (0.55) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5774563 | 0.76 | ALB (0.69) | ALBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15652097 | 0.74 | RAB9A (0.67) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |