Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515918 | 0.84 | NFE2L2 (0.52) | ALBKMT2AMEN1MAPTPOLB | |
| SCHEMBL5776476 | 0.84 | NFE2L2 (0.52) | ALBKMT2AMEN1MAPTPOLB | |
| SCHEMBL5774563 | 0.80 | ALB (0.69) | ALBKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5780106 | 0.80 | ALB (0.57) | ALBKMT2AMEN1MAPTPOLB | |
| SCHEMBL5779175 | 0.80 | ALB (0.55) | ALBKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5780400 | 0.80 | ALB (0.53) | ALBKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5778029 | 0.79 | ALB (0.51) | ALBKMT2AMEN1MAPTPOLB | |
| SCHEMBL5776363 | 0.76 | ALB (0.66) | ALBKMT2AMEN1MAPTNPC1 | |
| SCHEMBL5775071 | 0.75 | ALB (0.60) | ALBKMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL5779807 | 0.75 | ALB (0.61) | ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |