SCHEMBL193137

SCHEMBL193137

Cc1cc[c]c(-c2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.39
KDM4E B2RXH2 6/20 0.37
ALDH1A1 P00352 5/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
HPGD P15428 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 3/20 0.36
ACHE P22303 2/20 0.36
ALOX12 P18054 1/20 0.36
MAPT P10636 3/20 0.36
TP53 P04637 2/20 0.35
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CASP3 P42574 2/20 0.34
SENP8 Q96LD8 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
SENP6 Q9GZR1 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4125762 0.96 MAOB (0.37) MAOBKDM4EALDH1A1L3MBTL1NPC1
SCHEMBL5779452 0.85 ACHE (0.44) KDM4EALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL102139 0.84 TDP1 (0.36) MAOBKDM4EALDH1A1NPC1RAB9A
SCHEMBL8532142 0.84 GSTP1 (0.43) KDM4EALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL7049757 0.81 ACHE (0.38) ALDH1A1SMN1; SMN2LMNAACHETP53
SCHEMBL9706195 0.80 NPC1 (0.41) KDM4EALDH1A1L3MBTL1NPC1RAB9A
SCHEMBL9435986 0.80 ACHE (0.30) ACHE
SCHEMBL7138582 0.80 ACHE (0.36) ALDH1A1TSHRACHE
SCHEMBL1535844 0.79 ALDH1A1 (0.38) KDM4EALDH1A1NPC1RAB9AHPGD
SCHEMBL1491043 0.79 ACHE (0.41) MAOBALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 623 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024084490-A1 EMERGENCY RESCUE & AID SUPPORT SYSTEM - ERASS RAM KISHORE THANDAL MURALIRAJA (IN) 2024-04-25 WO claimed
US-11230526-B1 Cylcoalkenyl derivatives useful as agonists of the GPR120 and/or GPR40 receptors JANSSEN PHARMACEUTICA NV (BE) 2022-01-25 US claimed
US-20210024483-A1 HETEROCYLCOALKENYL DERIVATIVES USEFUL AS AGONISTS OF THE GPR120 AND / OR GPR40 JANSSEN PHARMACEUTICA NV (BE) 2021-01-28 US claimed
CN-111499543-A α -fluoroalkyl- β -amidoketone compound and preparation method thereof 南京工业大学 2020-08-07 CN claimed
CN-111484462-A 4-isoxazoline compound and preparation method thereof 南京工业大学 2020-08-04 CN claimed
CN-105264406-B Optical article comprising an acrylic substrate coated with a specific hard coating 依视路国际公司 2020-03-17 CN claimed
EP-3608329-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC Ireland Limited (IE) 2020-02-12 EP claimed
WO-2019171278-A1 HETEROCYLCOALKENYL DERIVATIVES USEFUL AS AGONISTS OF THE GPR120 AND / OR GPR40 JANSSEN PHARMACEUTICA NV (BE) 2019-09-12 WO claimed
WO-2019171277-A1 CYLCOALKENYL DERIVATIVES USEFUL AS AGONISTS OF THE GPR120 AND /OR GPR40 RECEPTORS JANSSEN PHARMACEUTICA NV (BE) 2019-09-12 WO claimed
CN-106340594-A White-light organic electroluminescent device and preparation method thereof 南京邮电大学 2017-01-18 CN claimed
US-4744000-A Electrical capacitor having improved dielectric system COOPER INDUSTRIES, INC. (US) 1988-05-10 US claimed
US-4742055-A ANTISECRETORY, ANTIULCER RORER PHARMACEUTICAL CORPORATION (US) 1988-05-03 US claimed
US-4503232-A FROM HALOHYDROCARBON, PRIMARY AMINE, AND CARBON MONOXIDE AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1985-03-05 US claimed
US-4401797-A ADDUCT OF DIHYDROXYPROPYL (METH)ACRYLATE AND BORONIC ACID SYNTEX (U.S.A.) INC. (US) 1983-08-30 US claimed
US-4397767-A METAL DEPOSITS ON CRACKING CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1983-08-09 US claimed
EP-0015856-B1 AROMATIC THERMOTROPIC COPOLYESTERS AND PROCESSES FOR THEIR PREPARATION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-11-24 EP claimed
US-4324648-A TO PERMIT REGENERATION OF CATALYST BY OXIDATION PHILLIPS PETROLEUM COMPANY (US) 1982-04-13 US claimed
EP-0036661-A1 Process for improving the properties of a cracking catalyst PHILLIPS PETROLEUM COMPANY (US) 1981-09-30 EP claimed
US-4143029-A HEXAKIS/ALKOXYMETHYL/MELAMINE, A TRIHYDROCARBYLCARBONYL MELAMINE, AND A BIS/MALEIMIDE UNIROYAL, INC. (US) 1979-03-06 US claimed
US-4090967-A FIREPROOFING CIBA-GEIGY CORPORATION (US) 1978-05-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024483-A1 HETEROCYLCOALKENYL DERIVATIVES USEFUL AS AGONISTS OF THE GPR120 AND / OR GPR40 GPR119, GPR65, GPR55 MAOB 3427/4885KDM4E 3453/4885ALDH1A1 3699/4885
US-11230526-B1 Cylcoalkenyl derivatives useful as agonists of the GPR120 and/or GPR40 receptors GPR119, GPR65, GPR55 MAOB 4468/4885KDM4E 2814/4885ALDH1A1 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.