Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769296 | 0.87 | SLC6A9 (0.52) | KMT2ASLC6A9OPRD1ALDH1A1CACNA2D1 | |
| SCHEMBL12154797 | 0.84 | KMT2A (0.56) | KMT2ASLC6A9OPRD1CYP3A4ALDH1A1 | |
| SCHEMBL7834836 | 0.83 | SLC6A9 (0.47) | KMT2ASLC6A9OPRD1CYP3A4ALDH1A1 | |
| SCHEMBL21641193 | 0.81 | CACNA2D1 (0.50) | KMT2ASLC6A9OPRD1CACNA2D1CACNA1B | |
| SCHEMBL21640152 | 0.81 | OPRD1 (0.49) | KMT2ASLC6A9OPRD1ALDH1A1MEN1 | |
| SCHEMBL7383336 | 0.80 | MTNR1A (0.50) | KMT2ASLC6A9OPRD1CYP3A4ALDH1A1 | |
| SCHEMBL17726230 | 0.80 | KMT2A (0.45) | KMT2ASLC6A9OPRD1CACNA2D1CACNA1B | |
| SCHEMBL20594076 | 0.80 | KMT2A (0.57) | KMT2ASLC6A9OPRD1CYP3A4ALDH1A1 | |
| SCHEMBL16759363 | 0.79 | SLC6A9 (0.46) | KMT2ASLC6A9OPRD1ALDH1A1CYP2D6 | |
| SCHEMBL85392 | 0.78 | OPRM1 (0.48) | KMT2ASLC6A9OPRD1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687296-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005049605-A1 | ANTIBACTERIAL AMINOQUINAZOLIDINEDIONE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |
| WO-2005049602-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-02 | — | — | WO | disclosed |