Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 9/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275069 | 0.82 | MPO (0.55) | MPOHRH3SLC6A4ALDH1A1TAAR1 | |
| SCHEMBL7043356 | 0.73 | ALDH1A1 (0.48) | MPOALDH1A1TAAR1GRIN2BBCHE | |
| SCHEMBL7111070 | 0.72 | ALDH1A1 (0.47) | MPOALDH1A1TAAR1GRIN2BBCHE | |
| SCHEMBL2093428 | 0.72 | GRIN2B (0.41) | HRH3ALDH1A1TAAR1GRIN2B | |
| SCHEMBL5779010 | 0.71 | CHRM3 (0.42) | HRH3TAAR1GRIN2B | |
| SCHEMBL2092320 | 0.68 | GRIN2B (0.54) | GRIN2BBCHEACHEBACE1 | |
| SCHEMBL1579038 | 0.68 | — | — | |
| SCHEMBL3121659 | 0.68 | KMT2A (0.66) | ALDH1A1BCHE | |
| SCHEMBL3034101 | 0.68 | HRH3 (0.43) | HRH3ALDH1A1GRIN2BCA12CA2 | |
| SCHEMBL10526958 | 0.67 | MPO (0.80) | MPOSLC6A4TAAR1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631570-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Abbott Laboratories (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | disclosed |