Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | UNG | P13051 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778185 | 0.88 | MMP1 (0.34) | LTA4HPLA2G2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5774639 | 0.79 | HPGD (0.47) | ALDH1A1KDM4E | |
| SCHEMBL5779417 | 0.75 | SETDB1 (0.42) | RAB9A | |
| SCHEMBL1935713 | 0.74 | MMP1 (0.46) | ALDH1A1KDM4ERAB9AMMP1MMP2 | |
| SCHEMBL28808632 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4EPTGS2RAB9APOLB | |
| SCHEMBL322186 | 0.74 | CYP1A2 (0.49) | LTA4HPLA2G2AMTNR1AMTNR1BRAB9A | |
| SCHEMBL2635612 | 0.72 | MMP1 (0.49) | MTNR1AMTNR1BALDH1A1UNGRAB9A | |
| SCHEMBL5912980 | 0.71 | MEN1 (0.36) | ALDH1A1POLB | |
| SCHEMBL5779948 | 0.70 | ALDH1A1 (0.33) | ALDH1A1UNGKDM4EPTGS2RAB9A | |
| SCHEMBL5912978 | 0.70 | POLB (0.33) | ALDH1A1MMP1MMP2MMP9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |