Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778185 | 0.82 | MMP1 (0.34) | HPGDALDH1A1KDM4E | |
| SCHEMBL3529974 | 0.81 | HPGD (0.67) | HPGDCNR1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL28753564 | 0.80 | HPGD (0.50) | HPGDCNR1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL5779953 | 0.79 | LTA4H (0.34) | ALDH1A1KDM4E | |
| SCHEMBL27611366 | 0.78 | HPGD (0.49) | HPGDCNR1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL23405003 | 0.77 | ALDH1A1 (0.53) | HPGDALDH1A1KDM4ETDP1 | |
| SCHEMBL14685938 | 0.75 | ALDH1A1 (0.47) | ALDH1A1PYGLKMT2AMEN1 | |
| SCHEMBL5110287 | 0.75 | P2RX7 (0.46) | HPGDCNR1ALDH1A1PLAAT3PLAAT5 | |
| SCHEMBL1935713 | 0.74 | MMP1 (0.46) | HPGDALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL27958719 | 0.74 | ALDH1A1 (0.53) | HPGDALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |