Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.55 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31577322 | 1.00 | ALOX5 (0.55) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL7476041 | 0.85 | ALOX5 (0.48) | ALOX5EPHX2ALDH1A1POLB | |
| SCHEMBL15524906 | 0.85 | KDM4E (0.43) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL15524922 | 0.82 | LMNA (0.41) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL15525689 | 0.80 | NR1H3 (0.44) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL28254836 | 0.79 | ALOX5 (0.47) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL15524910 | 0.78 | HDAC1 (0.42) | ALOX5EPHX2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL5782563 | 0.77 | ALOX5 (0.50) | ALOX5EPHX2KCNT1HDAC1HDAC6 | |
| SCHEMBL21237540 | 0.77 | NPC1 (0.50) | HDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL15524900 | 0.77 | HDAC1 (0.52) | ALOX5EPHX2KCNT1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264496-A1 | Substituted indoline and indole derivatives | H. LUNDBECK A/S (DK) | 2006-11-23 | — | — | US | disclosed |
| EP-1631546-A1 | SUSTITUTED INDOLINE AND INDOLE DERIVATIVES | H. Lundbeck A/S (DK) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004096767-A1 | SUSTITUTED INDOLINE AND INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264496-A1 | Substituted indoline and indole derivatives | IDO1, IDO2, INMT | ALOX5 2370/4885EPHX2 4540/4885KCNT1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.