Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24724656 | 0.89 | GAA (0.49) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL12801566 | 0.80 | LMNA (0.53) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL108862 | 0.79 | LMNA (0.56) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL6361527 | 0.77 | LMNA (0.50) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL11538276 | 0.76 | LMNA (0.53) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL11536851 | 0.75 | ALDH1A1 (0.49) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL11535313 | 0.75 | ALDH1A1 (0.48) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL11539400 | 0.74 | LMNA (0.48) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL11536831 | 0.74 | POLB (0.58) | GAAALDH1A1TDP1AGTR1LMNA | |
| SCHEMBL12292649 | 0.73 | LMNA (0.57) | GAAALDH1A1TDP1AGTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627870-A1 | CYANOFLUOROPYRROLIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | DPP4, DPP3, NPY4R | GAA 3526/4885ALDH1A1 3197/4885TDP1 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.