SCHEMBL11535313

SCHEMBL11535313

CCOC(=O)CNC(=O)c1snnc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
LMNA P02545 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
GAA P10253 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 3/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
PKM P14618 1/20 0.45
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.43
AGTR1 P30556 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12801566 0.80 LMNA (0.53) ALDH1A1LMNAGAATDP1NPC1
SCHEMBL6361527 0.78 LMNA (0.50) ALDH1A1LMNAGAATDP1NPC1
SCHEMBL11537526 0.77 LMNA (0.43) ALDH1A1LMNASMN1; SMN2GAATDP1
SCHEMBL24724656 0.76 GAA (0.49) ALDH1A1LMNAGAATDP1NPC1
SCHEMBL13528588 0.75 SMN1; SMN2 (0.53) ALDH1A1LMNASMN1; SMN2GAAHPGD
SCHEMBL2211256 0.75 MAPT (0.54) ALDH1A1LMNAGAAHPGDHSD17B10
SCHEMBL5780754 0.75 GAA (0.48) ALDH1A1LMNAGAATDP1NPC1
SCHEMBL11539400 0.75 LMNA (0.48) ALDH1A1LMNAGAATDP1NPC1
SCHEMBL108862 0.73 LMNA (0.56) ALDH1A1LMNAGAAKDM4ETDP1
SCHEMBL11536851 0.73 ALDH1A1 (0.49) ALDH1A1LMNAGAAKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177054-A PREEMERGENT AND POSTEMERGENT SCHERING AKTIENGESELLSCHAFT (DE) 1979-12-04 US claimed