Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782172 | 0.87 | CXCR1 (0.53) | MEN1KMT2APABPC1NNMTRAB9A | |
| SCHEMBL5782764 | 0.87 | NNMT (0.47) | MEN1KMT2APABPC1NNMTRAB9A | |
| SCHEMBL5594217 | 0.82 | KCNH2 (0.47) | MEN1KMT2AUSP2PABPC1NNMT | |
| SCHEMBL5783122 | 0.81 | RAB9A (0.48) | RAB9ASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL5421835 | 0.79 | MAPT (0.55) | MEN1KMT2APABPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1725895 | 0.78 | NNMT (0.54) | MEN1KMT2APABPC1NNMTRAB9A | |
| SCHEMBL31546343 | 0.78 | NNMT (0.54) | MEN1KMT2APABPC1NNMTRAB9A | |
| SCHEMBL21424948 | 0.77 | NPC1 (0.57) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL13947158 | 0.77 | SMN1; SMN2 (0.65) | MEN1KMT2AUSP2PABPC1RAB9A | |
| SCHEMBL5780823 | 0.74 | F2 (0.50) | MEN1KMT2ANNMTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | MEN1 2886/4885KMT2A 4143/4885USP2 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.