Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762307 | 0.83 | DCTPP1 (0.44) | DCTPP1NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL4868188 | 0.79 | DCTPP1 (0.38) | DCTPP1NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL4865551 | 0.76 | ADORA3 (0.39) | DCTPP1L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL4770686 | 0.73 | DCTPP1 (0.51) | DCTPP1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4767339 | 0.73 | HSPD1 (0.40) | DCTPP1NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL4867838 | 0.73 | ADORA2B (0.40) | DCTPP1ADORA3MAPTSMN1; SMN2GABRA5 | |
| SCHEMBL4763895 | 0.72 | MAPT (0.45) | DCTPP1L3MBTL1MEN1USP2POLB | |
| SCHEMBL4763887 | 0.72 | MAPT (0.45) | DCTPP1L3MBTL1MEN1USP2POLB | |
| SCHEMBL4894064 | 0.71 | ADORA2B (0.42) | DCTPP1ADORA3GABRA5TDP1 | |
| SCHEMBL4766012 | 0.71 | PDE4A (0.38) | DCTPP1L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678181-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042534-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |