Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | MAOA | P21397 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578354 | 0.82 | KDM4E (0.53) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL28410509 | 0.80 | KDM4E (0.52) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL10216424 | 0.80 | KDM4E (0.58) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL4757017 | 0.80 | LMNA (0.61) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL8802227 | 0.80 | KDM4E (0.59) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL33892 | 0.79 | CYP3A4 (0.59) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL2746872 | 0.79 | MEN1 (0.90) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL752884 | 0.77 | KDM4E (0.65) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| SCHEMBL2318320 | 0.77 | CA1 (0.65) | KDM4ECYP3A4MEN1KMT2AMAPK1 | |
| Flavonol SCHEMBL20246 | 0.77 | KDM4E (1.00) | KDM4ECYP3A4MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734693-A | A method of preparing 5,7- dihydroxy chromone | 昌邑市银江生物科技有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-104230868-B | A kind of chemical preparation process of compound 2-methyl-5,7-dihydroxyl chromone | SYNYOO NEW MATERIALS CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-105076915-A | Fat-soluble bamboo leaf antioxidant prepared by using enzymatic method and application thereof | HANGZHOU NINGZHU BIOTECHNOLOGY CO LTD | 2015-11-25 | — | — | CN | claimed |
| CN-104230868-A | Chemical preparation method of compound 2-methyl-5,7-dihydroxy chromone | GUANGDONG SYNYOO NEW MATERIALS COMPANY LTD | 2014-12-24 | — | — | CN | claimed |
| CN-102253145-B | Method for detecting 5,7-dyhydroxy chromone, eriodictyol and luteolin in peanut shell simultaneously | INST AGRO FOOD SHANDONG AAS | 2013-01-23 | — | — | CN | claimed |
| CN-102253145-A | Method for detecting 5,7-dyhydroxy chromone, eriodictyol and luteolin in peanut shell simultaneously | INST AGRO FOOD SCI & TECH SAAS | 2011-11-23 | — | — | CN | claimed |
| US-12053465-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118191150-A | Method for detecting polygonum capitatum formula particles | 贵州益佰制药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11925622-B2 | Role of novel carbazole linked 1, 2, 3- triazole analogs in alleviating methylglyoxal-mediated late diabetic vascular complications | JAHAN HUMERA (PK) | 2024-03-12 | — | — | US | disclosed |
| CN-111945420-B | Environment-friendly silver fiber fabric and preparation method thereof | 浙江木星实验科技有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-12-01 | — | — | US | disclosed |
| US-11331313-B2 | KCC2 expression enhancing compounds and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200085817-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2020-03-19 | — | — | US | disclosed |
| US-20070191305-A1 | Chromone complexes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |
| CN-1919229-A | Bauhinia hupehara C. extract for the treatment of diabetes and obesity | INST PHARM & TOXICOLOGY AMMS (CN) | 2007-02-28 | — | — | CN | disclosed |
| US-20060292093-A1 | Chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2006-12-28 | — | — | US | disclosed |
| EP-1656364-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005019197-A1 | CHROMEN-4-ONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043398-A1 | Use of chromen-4-one derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331313-B2 | KCC2 expression enhancing compounds and uses thereof | MECP2, SLC1A2, GRIN2C | KDM4E 127/4885CYP3A4 4721/4885MEN1 2772/4885 |
| US-20200085817-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | MECP2, SLC1A2, GRIN2C | KDM4E 127/4885CYP3A4 4721/4885MEN1 2772/4885 |
| US-20220378782-A1 | KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF | MECP2, SLC1A2, GRIN2C | KDM4E 127/4885CYP3A4 4721/4885MEN1 2772/4885 |
| US-20070191305-A1 | Chromone complexes | SCO2, CDYL, CYCS | KDM4E 2073/4885CYP3A4 335/4885MEN1 567/4885 |
| US-20050043398-A1 | Use of chromen-4-one derivatives | CYP8B1, CYP7B1, CYP2R1 | KDM4E 1606/4885CYP3A4 246/4885MEN1 2601/4885 |
| US-12053465-B2 | KCC2 expression enhancing compounds and uses thereof | MECP2, SLC1A2, GRIN2C | KDM4E 127/4885CYP3A4 4721/4885MEN1 2772/4885 |
| US-20060292093-A1 | Chromen-4-one derivatives | TYR, XPA, CYP19A1 | KDM4E 1205/4885CYP3A4 46/4885MEN1 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.