Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | LCAT | P04180 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387851 | 0.90 | PDE10A (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL389193 | 0.90 | PDE10A (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL387850 | 0.90 | PDE10A (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9537856 | 0.86 | AKR1C3 (0.44) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3913667 | 0.85 | PDE10A (0.48) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15206004 | 0.84 | AKR1C3 (0.52) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5236585 | 0.83 | AKR1C3 (0.61) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30018285 | 0.83 | AKR1C3 (0.51) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14127792 | 0.83 | GRIN2D (0.49) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14127793 | 0.83 | MAPT (0.57) | AKR1C3GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246961-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-07-25 | — | — | US | disclosed |
| US-11970493-B2 | Autotaxin inhibitor compounds | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-04-30 | — | — | US | disclosed |
| EP-4225756-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | Ildong Pharmaceutical Co., Ltd. (KR) | 2023-08-16 | — | — | EP | disclosed |
| CN-116322692-A | Autotaxin inhibitor compounds | 日东制药株式会社 | 2023-06-23 | — | — | CN | disclosed |
| US-11642348-B2 | Substituted benzene compounds | Epizyme, Inc. (US) | 2023-05-09 | — | — | US | disclosed |
| US-11642348-B2 | Substituted benzene compounds | Epizyme, Inc. (US) | 2023-05-09 | — | — | US | disclosed |
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022074459-A2 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | WO | disclosed |
| US-20220106311-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-07 | — | — | US | disclosed |
| EP-3725314-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| US-6521618-B2 | Antineoplastic agents, agents for treatment of osteoporosis and polycystic kidney disease | WYETH | 2003-02-18 | — | — | US | disclosed |
| EP-1268431-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2003-01-02 | — | — | EP | disclosed |
| US-20020026052-A1 | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-02-28 | — | — | US | disclosed |
| US-20020013460-A1 | Condensed pyridine compound | EISAI CO., LTD | 2002-01-31 | — | — | US | disclosed |
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| WO-2001094342-A1 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | DONG A PHARM. CO., LTD. (KR) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001072711-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-10-04 | — | — | WO | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0605524-A1 | ANTIBACTERIAL, ANTIMYCOPLASMAL COMPOUNDS RELATED TO MUPIROCIN | SMITHKLINE BEECHAM PLC (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993006118-A1 | ANTIBACTERIAL, ANTIMYCOPLASMAL COMPOUNDS RELATED TO MUPIROCIN | SMITHKLINE BEECHAM PLC (GB) | 1993-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013460-A1 | Condensed pyridine compound | MUSK, HTR1A, PAX3 | AKR1C3 3428/4885GRIN2D 910/4885GRIN3B 1322/4885 |
| US-20240246961-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, ATXN10, ATXN2L | AKR1C3 4360/4885GRIN2D 4723/4885GRIN3B 3816/4885 |
| US-20220106311-A1 | AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, ATXN10, ATXN2L | AKR1C3 4360/4885GRIN2D 4723/4885GRIN3B 3816/4885 |
| US-11970493-B2 | Autotaxin inhibitor compounds | ENPP2, ATXN10, ATXN2L | AKR1C3 4360/4885GRIN2D 4723/4885GRIN3B 3816/4885 |
| US-20020026052-A1 | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors | PKD1, PKD2, CSNK1A1 | AKR1C3 1978/4885GRIN2D 3006/4885GRIN3B 2132/4885 |
| US-11642348-B2 | Substituted benzene compounds | CYP1B1, TP53, VHL | AKR1C3 418/4885GRIN2D 4812/4885GRIN3B 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.