SCHEMBL578668

SCHEMBL578668

CCCC(C)(COC(N)=O)COC(=O)NCC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
HSD17B10 Q99714 1/20 0.68
TSHR P16473 2/20 0.63
CYP3A4 P08684 1/20 0.63
NFKB1 P19838 1/20 0.63
ADRA1A P35348 1/20 0.63
RAB9A P51151 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
EGLN1 Q9GZT9 2/20 0.36
ALOX15 P16050 1/20 0.32
PLA2G2A P14555 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041806 0.85 LMNA (0.45) LMNAHSD17B10TSHRCYP3A4NFKB1
SCHEMBL10041800 0.83 LMNA (0.68) LMNAHSD17B10TSHRCYP3A4NFKB1
Tybamate SCHEMBL78046 0.82 LMNA (0.68) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL20545451 0.82 LMNA (0.92) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL3056097 0.82 LMNA (1.00) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL15286 0.82 LMNA (1.00) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL18703920 0.81 LMNA (0.96) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL8913202 0.81 LMNA (0.96) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL7583576 0.81 LMNA (0.96) LMNAHSD17B10TSHRCYP3A4NFKB1
Meprobamate SCHEMBL29045066 0.81 LMNA (0.96) LMNAHSD17B10TSHRCYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418492-B1 Immunoreagent for meprobamate RANDOX LABORATORIES LTD (GB) 2018-10-10 EP disclosed
US-20120040378-A1 Meprobromate Immunoassay RANDOX LABORATORIES LIMITED (GB) 2012-02-16 US disclosed
US-20120040378-A1 Meprobromate Immunoassay RANDOX LABORATORIES LIMITED (GB) 2012-02-16 US disclosed
EP-2418492-A1 Meprobamate immunoassay Randox Laboratories Ltd. (GB) 2012-02-15 EP disclosed
EP-2418492-A1 Meprobamate immunoassay Randox Laboratories Ltd. (GB) 2012-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040378-A1 Meprobromate Immunoassay MEP1B, CES2, MEP1A LMNA 4619/4885HSD17B10 449/4885TSHR 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.