Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 5/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 5/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | LCT | P09848 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578711 | 1.00 | PDE4D (0.47) | PDE4DTAAR1UGCGGBA2GBA1 | |
| SCHEMBL578712 | 1.00 | PDE4D (0.47) | PDE4DTAAR1UGCGGBA2GBA1 | |
| SCHEMBL21374478 | 0.86 | PDE4D (0.47) | PDE4DTAAR1TSHRRENNAAA | |
| SCHEMBL6671511 | 0.86 | PDE4D (0.46) | PDE4DTSHRSLC6A2BCHEACHE | |
| SCHEMBL6669362 | 0.86 | PDE4D (0.46) | PDE4DTSHRSLC6A2BCHEACHE | |
| SCHEMBL9074021 | 0.86 | PDE4D (0.46) | PDE4DTSHRSLC6A2BCHEACHE | |
| SCHEMBL9074022 | 0.86 | PDE4D (0.46) | PDE4DTSHRSLC6A2BCHEACHE | |
| SCHEMBL6671515 | 0.86 | PDE4D (0.46) | PDE4DTSHRSLC6A2BCHEACHE | |
| SCHEMBL578467 | 0.82 | TAAR1 (0.40) | PDE4DTAAR1UGCGGBA2GBA1 | |
| SCHEMBL578468 | 0.82 | TAAR1 (0.40) | PDE4DTAAR1UGCGGBA2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418203-B1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2013-12-11 | — | — | EP | disclosed |
| US-8410273-B2 | Cyclic compound having substituted phenyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| EP-2418203-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | Daiichi Sankyo Company, Limited (JP) | 2012-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | BMP2, BMP4, BMP6 | PDE4D 2410/4885TAAR1 4648/4885UGCG 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.