SCHEMBL5787348

SCHEMBL5787348

NC(=O)CC[C@H](N)C(=O)N1CC=CC1C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 4/20 0.43
NRP1 O14786 3/20 0.40
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
KMT2A Q03164 1/20 0.40
ACE P12821 1/20 0.37
DPP4 P27487 6/20 0.35
DPP8 Q6V1X1 5/20 0.35
DPP9 Q86TI2 5/20 0.35
FAP Q12884 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
ARG1 P05089 1/20 0.34
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5789987 0.90 ACE (0.49) PIN1NRP1ALOX15BLMPMP22
SCHEMBL5789221 0.80 DPP4 (0.42) NRP1ALOX15BLMPMP22KMT2A
SCHEMBL6165300 0.79 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL6492871 0.79 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5791159 0.79 ALOX15 (0.37) PIN1NRP1ALOX15BLMPMP22
SCHEMBL6741429 0.79 ALOX15 (0.37) NRP1ALOX15BLMPMP22KMT2A
SCHEMBL5788597 0.79 ARG1 (0.37) NRP1ALOX15BLMPMP22KMT2A
SCHEMBL7418737 0.79 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5803785 0.76 PIN1 (0.36) PIN1ALOX15BLMPMP22KMT2A
SCHEMBL6742082 0.73 DPP7 (0.50) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622870-A2 GLUTAMINYL BASED DP IV-INHIBITORS Prosidion Ltd. (GB) 2006-02-08 EP disclosed
WO-2004099134-A2 GLUTAMINYL BASED DP IV-INHIBITORS PROSIDION LTD. (GB) 2004-11-18 WO disclosed
US-20040229848-A1 Glutaminyl based DP IV-inhibitors PROSIDION LIMITED (GB) 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229848-A1 Glutaminyl based DP IV-inhibitors DPP4, DPP3, DNPEP PIN1 452/4885NRP1 2446/4885ALOX15 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.