SCHEMBL5791159

SCHEMBL5791159

NC(=O)CC[C@H](N)C(=O)N1CC=CC1P(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
KMT2A Q03164 1/20 0.37
DPP4 P27487 7/20 0.33
DPP8 Q6V1X1 6/20 0.33
DPP9 Q86TI2 5/20 0.33
DPP7 Q9UHL4 3/20 0.33
FAP Q12884 2/20 0.33
PIN1 Q13526 2/20 0.33
ARG1 P05089 1/20 0.32
NRP1 O14786 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5803785 0.81 PIN1 (0.36) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL6742877 0.79 DPP8 (0.51) DPP4DPP8DPP7PIN1
SCHEMBL5787348 0.79 PIN1 (0.43) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5789987 0.78 ACE (0.49) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5789221 0.77 DPP4 (0.42) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL6165300 0.76 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7418737 0.76 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL5788597 0.76 ARG1 (0.37) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL6741429 0.76 ALOX15 (0.37) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL6492871 0.76 DPP7 (0.39) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622870-A2 GLUTAMINYL BASED DP IV-INHIBITORS Prosidion Ltd. (GB) 2006-02-08 EP disclosed
WO-2004099134-A2 GLUTAMINYL BASED DP IV-INHIBITORS PROSIDION LTD. (GB) 2004-11-18 WO disclosed
US-20040229848-A1 Glutaminyl based DP IV-inhibitors PROSIDION LIMITED (GB) 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229848-A1 Glutaminyl based DP IV-inhibitors DPP4, DPP3, DNPEP ALOX15 4131/4885BLM 3796/4885PMP22 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.