SCHEMBL578949

SCHEMBL578949

CCCCCCC(Oc1ccccc1)=C(C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47
PGGT1B P53609 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
FAAH O00519 6/20 0.46
PTGS2 P35354 1/20 0.44
EPHX2 P34913 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7217885 1.00 THRB (0.47) THRBFNTAFNTBPGGT1BZDHHC2
SCHEMBL3406771 1.00 THRB (0.47) THRBFNTAFNTBPGGT1BZDHHC2
SCHEMBL15648200 0.94 MEN1 (0.44) THRBFNTAFNTBPGGT1BZDHHC2
SCHEMBL7520648 0.87 CES2 (0.41) THRBZDHHC2CES2CES1FAAH
SCHEMBL7520639 0.87 CES2 (0.41) THRBZDHHC2CES2CES1FAAH
SCHEMBL6683174 0.84 ESRRB (0.39) TDP1MEN1KMT2A
SCHEMBL28736630 0.84 ZDHHC2 (0.46) THRBFNTAFNTBPGGT1BZDHHC2
SCHEMBL372286 0.84 ZDHHC2 (0.46) THRBFNTAFNTBPGGT1BZDHHC2
SCHEMBL10627272 0.81 ZDHHC2 (0.47) ZDHHC2CES2CES1FAAHEPHX2
SCHEMBL372285 0.81 THRB (0.46) THRBFNTAFNTBPGGT1BZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
CN-114651049-A Photocurable compositions containing high refractive index monomers for 3D printing applications 阿科玛法国公司 2022-06-21 CN claimed
WO-2021048628-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2021-03-18 WO claimed
EP-1177227-B1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORP (US) 2003-10-01 EP claimed
US-20020128417-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-09-12 US claimed
EP-1177227-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2002-02-06 EP claimed
US-20020007032-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-01-17 US claimed
US-20010056165-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2001-12-27 US claimed
US-6281319-B1 HYDRATABLE POLYMER SURGIDEV CORPORATION 2001-08-28 US claimed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO claimed
EP-3389560-B1 REFRACTIVE CORRECTOR INCORPORATING A CONTINUOUS CENTRAL PHASE ZONE AND PERIPHERAL PHASE DISCONTINUITIES, AND METHOD OF FORMING IT UNIV ROCHESTER (US) 2026-04-08 EP disclosed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US disclosed
US-12232951-B2 Optical material and method for modifying the refractive index UNIVERSITY OF ROCHESTER (US) 2025-02-25 US disclosed
US-12090043-B2 Vision correction with laser refractive index changes UNIVERSITY OF ROCHESTER (US) 2024-09-17 US disclosed
US-20010056165-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2001-12-27 US disclosed
US-6281319-B1 HYDRATABLE POLYMER SURGIDEV CORPORATION 2001-08-28 US disclosed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO disclosed
EP-1035142-A1 Acrylic copolymer materials suitable for ophthalmic devices Nidek Co., Ltd. (JP) 2000-09-13 EP disclosed