SCHEMBL7520648

SCHEMBL7520648

CCCC(Oc1ccccc1)=C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ELANE P08246 2/20 0.40
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
FAAH O00519 4/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
ALOX5 P09917 1/20 0.38
HSP90AA1 P07900 1/20 0.38
GAA P10253 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520639 1.00 CES2 (0.41) CES2CES1ELANEMAPTALDH1A1
SCHEMBL15648200 0.90 MEN1 (0.44) CES2CES1KMT2AL3MBTL1ZDHHC2
SCHEMBL3406771 0.87 THRB (0.47) CES2CES1KMT2AZDHHC2FAAH
SCHEMBL7217885 0.87 THRB (0.47) CES2CES1KMT2AZDHHC2FAAH
SCHEMBL578949 0.87 THRB (0.47) CES2CES1KMT2AZDHHC2FAAH
SCHEMBL440972 0.86 ELANE (0.45) ELANEMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL15254 0.86 ELANE (0.45) ELANEMAPTALDH1A1HPGDSMN1; SMN2
Benzene SCHEMBL27375213 0.86 ELANE (0.45) ELANEMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL6135504 0.84 CES2 (0.42) CES2CES1ELANEMAPTALDH1A1
SCHEMBL15313245 0.84 SMN1; SMN2 (0.44) ELANEMAPTALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed
US-10670796-B2 Organic-inorganic hybrid composition, optical member and optical device prepared using the same LMS CO., LTD. (KR) 2020-06-02 US disclosed
US-20160070053-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, OPTICAL MEMBER AND OPTICAL DEVICE PREPARED USING THE SAME LMS CO., LTD. (KR) 2016-03-10 US disclosed
US-20150198740-A1 ORGANIC-INORGANIC HYBRID COMPOSITION, PRODUCTION METHOD FOR SAME, AND OPTICAL SHEET AND OPTICAL DEVICE OF SAME CHANGKANG CHEMICAL CO., LTD. (KR) 2015-07-16 US disclosed