Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25291736 | 0.89 | LMNA (0.64) | LMNATMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL5301158 | 0.84 | CHKA (0.58) | LMNASMN1; SMN2TSHRHPGDLTA4H | |
| SCHEMBL28287211 | 0.84 | SIGMAR1 (0.60) | LMNATMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL5790255 | 0.83 | PRKDC (0.54) | LMNAPKMHPGDMAPTMEN1 | |
| SCHEMBL4689823 | 0.83 | ALDH1A1 (0.52) | LMNASMN1; SMN2ADRA2CTSHRMAPT | |
| SCHEMBL11504798 | 0.82 | ALDH1A1 (0.46) | LMNASMN1; SMN2HPGDLTA4HMAPT | |
| SCHEMBL28198974 | 0.82 | CHKA (0.56) | LMNASMN1; SMN2TSHRHPGDLTA4H | |
| SCHEMBL27425605 | 0.82 | MAPT (0.44) | LMNATMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL28121639 | 0.81 | ALDH1A1 (0.46) | LMNASMN1; SMN2PKMTSHRHPGD | |
| SCHEMBL2555823 | 0.81 | LMNA (0.95) | LMNASIGMAR1SMN1; SMN2PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012683-A1 | CHEMICAL PROCESSES AND COMPOUNDS DERIVED THEREFROM | MONASH UNIVERSITY (AU) | 2006-02-09 | — | — | WO | claimed |