Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | GPR39 | O43194 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742735 | 0.92 | MAPT (0.64) | HRH4MAPTGFERHRH3CRHBP | |
| SCHEMBL5788994 | 0.87 | HRH4 (0.53) | HRH4MAPTGFERHRH3CRHBP | |
| SCHEMBL5743624 | 0.86 | SMPD3 (0.53) | HRH4HRH3SMPD3DHFR | |
| SCHEMBL5790678 | 0.83 | HRH4 (0.54) | HRH4MAPTGFERHRH3CRHBP | |
| SCHEMBL5743990 | 0.78 | DHFR (0.53) | HRH4MAPTGFERHRH3SMPD3 | |
| SCHEMBL606508 | 0.78 | HRH4 (0.60) | HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL5743802 | 0.77 | DHFR (0.52) | HRH4MAPTGFERHRH3SMPD3 | |
| SCHEMBL5789047 | 0.76 | HRH4 (0.66) | HRH4MAPTGFERHRH3CRHBP | |
| SCHEMBL31646673 | 0.76 | ALDH1A1 (0.46) | MAPTGFERSMN1; SMN2DHFRGPR39 | |
| SCHEMBL5742555 | 0.75 | MAPT (0.97) | HRH4MAPTGFERHRH3CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | claimed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| WO-2006016014-A1 | NOVEL COMPOUNDS OF A 6-METHYL-PYRIMIDINE-2,4-DIAMINE FAMILY, METHOD FOR SYNTHESISING, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | L'OREAL (FR) | 2006-02-16 | — | — | WO | disclosed |
| EP-1437348-A1 | 6-methyl-2,4-diamino-pyrimidine derivatives, process for preparation, compositions containing them and their uses as basic neutralising agents | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |