Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
| ▸ | GPR4 | P46093 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320226 | 0.90 | CTSK (0.47) | CTSKGPR4FGFR4GPR119XDH | |
| SCHEMBL5792575 | 0.82 | CTSK (0.44) | CTSKGPR4FGFR4XDH | |
| SCHEMBL5794380 | 0.80 | FGFR4 (0.41) | CTSKGPR4FGFR4GPR119XDH | |
| SCHEMBL5791034 | 0.79 | CTSK (0.42) | CTSKGPR4FGFR4XDH | |
| SCHEMBL5793393 | 0.77 | CTSK (0.41) | CTSKGPR4FGFR4XDH | |
| SCHEMBL5793788 | 0.76 | CTSK (0.38) | CTSKGPR4GPR119 | |
| SCHEMBL5791444 | 0.76 | CTSK (0.40) | CTSKGPR4FGFR4XDH | |
| SCHEMBL8270004 | 0.76 | CTSK (0.40) | CTSKGPR4FGFR4GPR119 | |
| SCHEMBL3313617 | 0.76 | CTSK (0.58) | CTSKGPR4FGFR4GPR119 | |
| SCHEMBL5794663 | 0.75 | CTSK (0.39) | CTSKGPR4FGFR4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |