Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270028 | 0.85 | GPR119 (0.37) | CTSKGPR119FGFR4AAK1GPR4 | |
| SCHEMBL5794364 | 0.85 | GPR119 (0.37) | CTSKGPR119FGFR4AAK1GPR4 | |
| SCHEMBL8270738 | 0.81 | CTSK (0.33) | CTSKGPR119FGFR4AAK1 | |
| SCHEMBL5794380 | 0.80 | FGFR4 (0.41) | CTSKGPR119FGFR4AAK1GPR4 | |
| SCHEMBL5307004 | 0.79 | CTSL (0.42) | CTSKGPR119AAK1 | |
| SCHEMBL3320226 | 0.79 | CTSK (0.47) | CTSKGPR119FGFR4GPR4HCRTR1 | |
| SCHEMBL5791037 | 0.78 | CTSK (0.42) | CTSKGPR119FGFR4AAK1GPR4 | |
| SCHEMBL5815642 | 0.78 | CTSK (0.40) | CTSKGPR119GPR4 | |
| SCHEMBL5792575 | 0.77 | CTSK (0.44) | CTSKFGFR4GPR4HCRTR1HCRTR2 | |
| SCHEMBL8270739 | 0.77 | CTSK (0.35) | CTSKGPR119HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |