Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | DTYMK | P23919 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297769 | 0.80 | MAPT (0.60) | MAPTDTYMKHCAR3ALDH1A1KDM4E | |
| SCHEMBL31338514 | 0.80 | MAPT (0.60) | MAPTDTYMKHCAR3ALDH1A1KDM4E | |
| SCHEMBL6081366 | 0.79 | HCAR3 (0.54) | MAPTDTYMKHCAR3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL591231 | 0.78 | MMP14 (0.42) | MAPTDTYMKHCAR3MMP14ALDH1A1 | |
| SCHEMBL5792361 | 0.78 | MAPT (0.47) | MAPTALDH1A1GAAKDM4EPOLB | |
| SCHEMBL27785428 | 0.76 | HCAR3 (0.44) | MAPTDTYMKHCAR3MMP14ALDH1A1 | |
| SCHEMBL7497984 | 0.75 | DTYMK (0.51) | MAPTDTYMKHCAR3ALDH1A1AKR1C3 | |
| SCHEMBL11158183 | 0.75 | KAT8 (0.55) | MAPTDTYMKHCAR3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL590351 | 0.75 | HCAR3 (0.43) | MAPTDTYMKHCAR3MMP14ALDH1A1 | |
| SCHEMBL8381314 | 0.74 | MAPT (0.56) | MAPTDTYMKALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |