Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779281 | 0.88 | MAPT (0.47) | MAPTALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL6790825 | 0.80 | ALDH1A1 (0.43) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL17774956 | 0.79 | IKBKB (0.41) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL5791745 | 0.78 | MAPT (0.56) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL297278 | 0.77 | KDM4E (0.57) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL11545057 | 0.76 | S100B (0.56) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| Hydrochloric Acid SCHEMBL3016561 | 0.76 | KMT2A (0.58) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| Hydrochloric Acid SCHEMBL1323656 | 0.76 | KMT2A (0.58) | MAPTALDH1A1CDC25BCASP6RCE1 | |
| SCHEMBL9458908 | 0.74 | MAPT (0.54) | MAPTALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL1082978 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1CDC25BCASP6RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |