Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947456 | 0.88 | MAPT (0.54) | P2RX3P2RX2MAPTWDR5 | |
| SCHEMBL1568296 | 0.87 | WDR5 (0.50) | P2RX3P2RX2ALDH1A1MAPTLMNA | |
| SCHEMBL13947315 | 0.86 | POLB (0.56) | P2RX3P2RX2NPC1POLBRAB9A | |
| SCHEMBL18617526 | 0.84 | MAPT (0.51) | P2RX3P2RX2HPGDALDH1A1MAPT | |
| SCHEMBL10263733 | 0.83 | WDR5 (0.48) | P2RX3P2RX2WDR5 | |
| SCHEMBL11962909 | 0.82 | MAPT (0.44) | P2RX3P2RX2HPGDALDH1A1MAPT | |
| SCHEMBL10203249 | 0.82 | WDR5 (0.47) | P2RX3P2RX2LMNAPOLBWDR5 | |
| SCHEMBL13450235 | 0.80 | EPHX2 (0.52) | P2RX3P2RX2MAPTWDR5KDM4E | |
| SCHEMBL14562163 | 0.80 | GABRA5 (0.51) | P2RX3P2RX2ALDH1A1NPC1LMNA | |
| SCHEMBL21875108 | 0.80 | PKM (0.52) | P2RX3P2RX2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592070-A2 | Tetrazole-substituted arylamides | F. Hoffmann-La Roche AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2006011719-A1 | N-SUBSTITUTED-SULFAMOYLBENZOIC ACID DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | B & C BIOPHARM CO., LTD. (KR) | 2006-02-02 | — | — | WO | disclosed |