Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795139 | 0.85 | ALDH1A1 (0.45) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL28904396 | 0.85 | CA1 (0.49) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL28479304 | 0.79 | CA1 (0.53) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL19204912 | 0.77 | L3MBTL1 (0.45) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL5794254 | 0.77 | NPSR1 (0.41) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL7641128 | 0.75 | RAPGEF4 (0.61) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL17397399 | 0.75 | CA1 (0.49) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL19204867 | 0.75 | L3MBTL1 (0.43) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL12696218 | 0.74 | CA1 (0.49) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL7317576 | 0.72 | ALDH1A1 (0.54) | L3MBTL1POLBHTTALDH3A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950083-A | Novel pyrrolo (2,3-b)pyridine derivatives, the preparation and the pharmaceutical use thereof in the form of kinase inhibitors | AVENTIS PHARMA SA (FR) | 2007-04-18 | — | — | CN | disclosed |
| EP-1732546-A2 | NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005095399-A2 | NOVEL PYRROLO (2,3-B)PYRIDINE DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF IN THE FORM OF KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2005-10-13 | — | — | WO | disclosed |