Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633406 | 0.80 | NOS1 (0.51) | LMNAALDH1A1KDM4ENOS3NOS1 | |
| SCHEMBL10503336 | 0.78 | MAOB (0.67) | L3MBTL1MEN1KMT2A | |
| SCHEMBL30282672 | 0.77 | NOS3 (0.55) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL25153702 | 0.77 | NOS3 (0.55) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL29114117 | 0.76 | NOS3 (0.54) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL30613110 | 0.76 | NOS3 (0.54) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL341673 | 0.74 | LMNA (0.85) | LMNAALDH1A1KDM4EHPGDLOXL2 | |
| SCHEMBL29447076 | 0.74 | NOS1 (0.61) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL244237 | 0.74 | NOS1 (0.61) | LMNAALDH1A1KDM4EHPGDNOS3 | |
| SCHEMBL9131214 | 0.74 | NOS1 (0.51) | LMNAALDH1A1KDM4EHPGDNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010968-A1 | NEW ARYLOXY ACETIC ACID AMIDE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |