Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.78 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9063654 | 0.98 | ADRA1A (0.76) | ADRA1ADRD2DRD3CYP1A2KDM1A | |
| SCHEMBL24734855 | 0.88 | ADRA1A (1.00) | ADRA1ADRD2DRD3CYP1A2HTR1D | |
| SCHEMBL31143007 | 0.86 | ADRA1A (0.78) | ADRA1ADRD2DRD3KDM1A | |
| Hydrochloric Acid SCHEMBL8669188 | 0.86 | ADRA1A (0.96) | ADRA1ADRD2DRD3CYP1A2HTR1D | |
| Bromide SCHEMBL25243558 | 0.86 | ADRA1A (0.96) | ADRA1ADRD2DRD3CYP1A2HTR1D | |
| Hydrochloric Acid SCHEMBL30861222 | 0.86 | ADRA1A (0.96) | ADRA1ADRD2DRD3CYP1A2HTR1D | |
| SCHEMBL7549300 | 0.81 | ADRA1A (0.78) | ADRA1ADRD2DRD3CYP1A2 | |
| SCHEMBL4217393 | 0.81 | ADRA1A (0.78) | ADRA1ADRD2DRD3CYP1A2 | |
| SCHEMBL867845 | 0.78 | ADRA1A (1.00) | ADRA1ADRD2DRD3CYP1A2 | |
| SCHEMBL25757255 | 0.78 | ADRA1A (0.59) | ADRA1ADRD2DRD3KDM1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651637-A1 | 3-AMINO CHROMAN AND 2-AMINO TETRALIN DERIVATIVES | Wyeth (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20050032873-A1 | 3-Amino chroman and 2-amino tetralin derivatives | WYETH (US) | 2005-02-10 | — | — | US | disclosed |
| WO-2005012291-A1 | 3-AMINO CHOMAN AND 2-AMINO TETRALIN DERIVATIVES | WYETH (US) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032873-A1 | 3-Amino chroman and 2-amino tetralin derivatives | TPH2, HTR2C, HTR7 | ADRA1A 493/4885DRD2 61/4885DRD3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.