Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.60 |
| ▸ | GNRHR | P30968 | 3/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387632 | 0.93 | RXRA (0.59) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL2390578 | 0.92 | RXRA (0.60) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL2387871 | 0.91 | RXRA (0.65) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL5598435 | 0.90 | RXRA (0.51) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL2389400 | 0.90 | RXRA (0.64) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL2389134 | 0.88 | RXRA (0.62) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL5597871 | 0.87 | RXRA (0.54) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL2389050 | 0.86 | RXRA (0.66) | RXRANR1H2NR1H3GNRHRRET | |
| SCHEMBL5615072 | 0.84 | RXRA (0.69) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL2386448 | 0.84 | RXRA (0.64) | RXRANR1H2NR1H3GNRHRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025979-A9 | MODULATORS OF NUCLEAR RECEPTORS | EXELIXIS INC (US) | 2006-04-20 | — | — | WO | disclosed |