Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807653 | 0.80 | CTSK (0.35) | CTSKGPR4FGFR4 | |
| SCHEMBL5794212 | 0.79 | HPGD (0.41) | CTSKGPR4FGFR4 | |
| SCHEMBL5791587 | 0.79 | MEN1 (0.36) | CTSKFGFR4GPR119 | |
| SCHEMBL5792562 | 0.78 | CTSK (0.45) | CTSKFGFR4 | |
| SCHEMBL5791044 | 0.78 | CTSK (0.45) | CTSKGPR4FGFR4 | |
| SCHEMBL5793159 | 0.78 | CTSK (0.36) | CTSKGPR4FGFR4 | |
| SCHEMBL5791288 | 0.78 | MAPK14 (0.43) | CTSKFGFR4 | |
| Trifluoroacetic Acid SCHEMBL5793434 | 0.77 | CTSK (0.44) | CTSKFGFR4 | |
| SCHEMBL8270721 | 0.77 | CTSK (0.41) | CTSKGPR4FGFR4GPR119 | |
| Trifluoroacetic Acid SCHEMBL5791892 | 0.75 | CTSK (0.38) | CTSKFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |