Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | GPR4 | P46093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792562 | 0.83 | CTSK (0.45) | CTSKFGFR4 | |
| SCHEMBL5791587 | 0.82 | MEN1 (0.36) | CTSKFGFR4 | |
| SCHEMBL5793909 | 0.80 | CTSK (0.41) | CTSKFGFR4GPR4 | |
| SCHEMBL5794212 | 0.80 | HPGD (0.41) | CTSKFGFR4GPR4 | |
| SCHEMBL5793159 | 0.78 | CTSK (0.36) | CTSKFGFR4GPR4 | |
| SCHEMBL5791288 | 0.78 | MAPK14 (0.43) | CTSKFGFR4 | |
| SCHEMBL5792625 | 0.77 | CTSK (0.37) | CTSKFGFR4GPR4 | |
| Trifluoroacetic Acid SCHEMBL5793434 | 0.76 | CTSK (0.44) | CTSKFGFR4 | |
| SCHEMBL5791044 | 0.75 | CTSK (0.45) | CTSKFGFR4GPR4 | |
| Trifluoroacetic Acid SCHEMBL5808826 | 0.75 | CTSK (0.37) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |