Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | GPR4 | P46093 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794212 | 0.90 | HPGD (0.41) | CTSKFGFR4KMT2ARAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5793434 | 0.83 | CTSK (0.44) | CTSKFGFR4KMT2ACTSLCTSS | |
| SCHEMBL5792562 | 0.79 | CTSK (0.45) | CTSKFGFR4KMT2ARAB9AALDH1A1 | |
| SCHEMBL8270011 | 0.79 | ALDH1A1 (0.39) | CTSKFGFR4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5807653 | 0.78 | CTSK (0.35) | CTSKFGFR4GPR4 | |
| SCHEMBL5793909 | 0.78 | CTSK (0.41) | CTSKFGFR4GPR4 | |
| Trifluoroacetic Acid SCHEMBL5791291 | 0.77 | CTSK (0.38) | CTSKKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5808749 | 0.76 | CACNA1G (0.37) | CTSKFGFR4CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5791288 | 0.76 | MAPK14 (0.43) | CTSKFGFR4NPC1RAB9A | |
| SCHEMBL5791587 | 0.75 | MEN1 (0.36) | CTSKFGFR4KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |