Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793066 | 0.75 | DRD2 (0.41) | DRD2DRD3DRD4MAP2K1ALDH1A1 | |
| SCHEMBL5794048 | 0.74 | ACKR3 (0.51) | DRD2DRD3DRD4IDO1 | |
| SCHEMBL3089935 | 0.71 | MTNR1A (0.34) | ALDH1A1 | |
| SCHEMBL3104390 | 0.71 | MTNR1A (0.34) | ALDH1A1 | |
| SCHEMBL12474432 | 0.70 | GAA (0.47) | ALDH1A1 | |
| SCHEMBL15064460 | 0.69 | HDAC3 (0.43) | ALDH1A1 | |
| SCHEMBL7300040 | 0.68 | PREP (0.51) | ALDH1A1 | |
| SCHEMBL2298237 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1974494 | 0.67 | HSD17B10 (0.38) | — | |
| SCHEMBL20378328 | 0.67 | HSD17B10 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |