Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074529 | 0.82 | KDM4E (0.48) | GPR17ALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL14602590 | 0.77 | ALDH1A1 (0.63) | ALDH1A1HSD17B10HTTUSP2MAPT | |
| SCHEMBL5592328 | 0.73 | NR4A2 (0.49) | HTTMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6049264 | 0.72 | GABRA1 (0.51) | ALDH1A1HSD17B10HTTUSP2MAPT | |
| SCHEMBL14174307 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HTTUSP2MAPT | |
| SCHEMBL486746 | 0.71 | KMT2A (0.46) | ALDH1A1HSD17B10HTTMAPTHPGD | |
| SCHEMBL3964313 | 0.70 | HRH4 (0.52) | ALDH1A1HSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL8795113 | 0.69 | MAP3K5 (0.48) | GPR17ALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL29620239 | 0.69 | KMT2A (0.47) | ALDH1A1HSD17B10HTTMAPTHPGD | |
| SCHEMBL24358283 | 0.69 | KMT2A (0.47) | ALDH1A1HSD17B10HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034480-A2 | SULFONAMIDE BICYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |