Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794395 | 0.87 | RXRA (0.40) | RXRARXRBRXRGKDM4EMEN1 | |
| SCHEMBL2089203 | 0.78 | MEN1 (0.46) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL5794771 | 0.75 | FSCN1 (0.43) | KDM4EALDH1A1LMNAHTTTSHR | |
| SCHEMBL5795378 | 0.75 | SIGMAR1 (0.53) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2089199 | 0.75 | MAPT (0.41) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL10942163 | 0.73 | MAPT (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1027463 | 0.72 | TDP1 (0.46) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL5797620 | 0.72 | LMNA (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL351155 | 0.69 | CYP1A2 (0.50) | RXRARXRBRXRGKDM4EALDH1A1 | |
| SCHEMBL20120182 | 0.66 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | disclosed |