Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942138 | 0.82 | DDB1 (0.40) | ALDH1A1SMN1; SMN2KDM4EFAAHPHGDH | |
| SCHEMBL2096466 | 0.81 | HSD17B1 (0.50) | HSD17B1HSD17B2ALDH1A1GAASTS | |
| SCHEMBL10944592 | 0.81 | MAPT (0.44) | ALDH1A1SIGMAR1SMN1; SMN2FAAHPHGDH | |
| SCHEMBL2096463 | 0.78 | HSD17B1 (0.53) | HSD17B1HSD17B2GAASTSSIGMAR1 | |
| SCHEMBL5797620 | 0.78 | LMNA (0.40) | ALDH1A1MAPTLMNA | |
| SCHEMBL22699132 | 0.76 | MAPT (0.44) | HSD17B1HSD17B2ALDH1A1GAASTS | |
| SCHEMBL2091852 | 0.75 | HSD17B1 (0.45) | HSD17B1HSD17B2ALDH1A1GAASTS | |
| SCHEMBL5795609 | 0.74 | CFD (0.37) | GAAFAAHPHGDHMGLLCA12 | |
| SCHEMBL14291898 | 0.74 | HSD17B1 (0.44) | HSD17B1HSD17B2STSSMN1; SMN2ESR1 | |
| SCHEMBL2091850 | 0.74 | HSD17B1 (0.44) | HSD17B1HSD17B2ALDH1A1STSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |