Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798129 | 0.83 | TSHR (0.39) | POLBGAAFAAHPHGDHMGLL | |
| SCHEMBL10946000 | 0.82 | POLB (0.42) | POLBGPBAR1FAAHPHGDHMGLL | |
| SCHEMBL5797620 | 0.81 | LMNA (0.40) | POLB | |
| SCHEMBL20844391 | 0.78 | GAA (0.43) | CFDNOTUMGAACYP11B1CYP11B2 | |
| SCHEMBL5798051 | 0.76 | FAAH (0.41) | POLBGAAFAAHPHGDHMGLL | |
| SCHEMBL27937999 | 0.76 | GPBAR1 (0.46) | POLBGPBAR1 | |
| SCHEMBL8525837 | 0.76 | CYP1A2 (0.36) | CFDNOTUMGAAPTGIRKMO | |
| SCHEMBL10942138 | 0.75 | DDB1 (0.40) | POLBGPBAR1FAAHPHGDHMGLL | |
| SCHEMBL5794697 | 0.74 | HSD17B1 (0.44) | GAAFAAHPHGDHMGLLCA12 | |
| SCHEMBL27938010 | 0.74 | GPBAR1 (0.44) | POLBGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |