Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023327 | 0.74 | HSD17B10 (0.41) | FABP4HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL4024437 | 0.74 | HSD17B10 (0.46) | FABP4HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL6691286 | 0.71 | FABP4 (0.61) | FABP4 | |
| SCHEMBL5794726 | 0.68 | ALDH1A1 (0.39) | FABP4HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL7415790 | 0.65 | PARP1 (0.43) | GALK1HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL7122377 | 0.65 | FABP4 (0.51) | FABP4HPGDALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7176265 | 0.65 | CNR1 (0.43) | FABP4HSD17B10KDM4EALDH1A1KMT2A | |
| SCHEMBL4029927 | 0.64 | SCARB1 (0.43) | FABP4HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL4025431 | 0.64 | SCARB1 (0.46) | FABP4HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL6756508 | 0.64 | SCARB1 (0.63) | FABP4HSD17B10HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |