Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765677 | 0.87 | DHFR (0.50) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5764905 | 0.85 | DHFR (0.48) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5765335 | 0.77 | DHFR (0.54) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5793347 | 0.75 | DHFR (0.50) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5766061 | 0.75 | DHFR (0.53) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5793452 | 0.74 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5911456 | 0.72 | DHFR (0.41) | ALDH1A1DHFRCA1CA2LMNA | |
| SCHEMBL5766967 | 0.72 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5766870 | 0.70 | DHFR (0.47) | ALDH1A1SMN1; SMN2DHFRCA1CA2 | |
| SCHEMBL5765442 | 0.68 | CACNA1C (0.44) | ALDH1A1SMN1; SMN2DHFRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | LG LIFE SCIENCES LTD. (KR) | 2006-06-01 | — | — | US | disclosed |
| EP-1633725-A1 | HEPATITIS C VIRUS INHIBITORS | LG Life Sciences Ltd. (KR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111013-A1 | HEPATITIS C VIRUS INHIBITORS | LG LIFE SCIENCES LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | HAVCR2, LIPC, FABP1 | ALDH1A1 1058/4885SMN1; SMN2 4724/4885DHFR 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.